Thanks for the article, looks like that one is from 2016. I'll share another article I found with a quick search -- "Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars" : https://pubmed.ncbi.nlm.nih.gov/29844096/
Now I'm not so sure which is the "primary driver". There are quite a few competing thoughts but maybe the point is you should lower both. That's probably one reason many docs (including mine in the past) recommend cutting both.
> Now I'm not so sure which is the "primary driver". There are quite a few competing thoughts but maybe the point is you should lower both.
On that I don't think we disagree.
However, saturated fat on its own isn't super palatable. There was a community I discovered a few years ago deliberately trying to up their saturated fat intake (specifically steric acid) and on it's own it's about as pleasurable as chewing on a candlestick (steric acid is used as a stiffener in paraffin candles).
One thing I remember seeing too is that inflammation increases damage caused by de novo lipogenesis. I am wondering if consumption of stable saturated fats vs. consumption of unstable (and commonly rancid polyunsaturated fats) exasperates things.
Now I'm not so sure which is the "primary driver". There are quite a few competing thoughts but maybe the point is you should lower both. That's probably one reason many docs (including mine in the past) recommend cutting both.