I can't help but think if you're willing to go this far for performance, then you'd simply choose another language over PHP (or even HipHop).
With this you loose the flexibility and transparency of having the framework in PHP. There have been many times when I've had to go routing through Zend framework to really understand how or why to do something a certain way.
With this you loose the flexibility and transparency of having the framework in PHP. There have been many times when I've had to go routing through Zend framework to really understand how or why to do something a certain way.