I was intrigued when my son had paradoxical reactions to GABA analogues so dug more into this (also has paradoxical reactions to benadryl, which is a different can of worms).
I think ASD, ADHD etc are all linked in terms of neurotransmitters and ion channel imbalance that causes overload on various pathways.
On interesting element on auditory processing is the similarities between ASD auditory sensitivity and hypokalemic sensory overload. Anecdotally I have seen dosing potassium reducing auditory sensitivity short term for possibly this reason.
Thanks for the link. I've read the first few pages: it's a really good read! Will definitely be reading this on the weekend.
On the paradoxical reaction to benadryl, and this is completely amateur speculation on my part, I wonder if it's because of benadryls anticholinergic effects (combined with a greater sensitivity, lower threshold etc.) resulting in a pseudo-anticholineric toxicity? And thereby outweighing the more typical effects of H1 anti-histamines? (disclaimer: I am very not a doctor, and this stuff is mostly beyond me)
I was intrigued when my son had paradoxical reactions to GABA analogues so dug more into this (also has paradoxical reactions to benadryl, which is a different can of worms).
I think ASD, ADHD etc are all linked in terms of neurotransmitters and ion channel imbalance that causes overload on various pathways.
On interesting element on auditory processing is the similarities between ASD auditory sensitivity and hypokalemic sensory overload. Anecdotally I have seen dosing potassium reducing auditory sensitivity short term for possibly this reason.