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"Say you discover data that leads you to suggest a different vaccination procedure."

There are plenty of examples of how accepted treatment is hard to shake. Take for example ^stomach ulcers^. Barry Marshall conducted self experiments to prove the H. pylori theory. The initial work started in '82. Marshall/Warren won the Nobel prize in 2005 [0] for this work. It changed the way stomach ulcers were understood and the treatment.

[0] https://en.wikipedia.org/wiki/Barry_Marshall



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