No. And can we please stop talking about "graceful degradation" and start talking about "progressive enhancement"? If accessibility isn't your first concern, you're doing something wrong (with some obvious exceptions -- building an online image editor for the blind is probably taking the accessibility thing a bit too far).
If accessibility is a higher priority than quality or even getting the product finished, you're doing something wrong. Losing accessibility is bad, but having something people don't want to access is worse.
