My experience in this realm:

Out of curiosity, in June or July I ran some Ethereum mining stuff on Azure's GPU instances.

The ROI was around -90% (negative 90%, to be clear: for $1 spent, I mined ~$0.10). Even with the higher price of Ethereum now, you'd probably be around that same ROI since the difficulty has also increased a fair amount.

usually most popular coins are not profitable to mining due to increased difficulty. i would suggest to try http://whattomine.com/ to decide.

I was making $30 or so a day profit mining Ethereum at home at this time, so there was plenty of profit out there, just not with the cloud GPU stuff.