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The literature points to R-ketamine, on it's own, appearing to have stronger antidepressant effect, with less of the disassociative effects.

AFAICT, it's not patentable, so nobody would pay for the trials.



This is very true . R-ketamine holds most of the benefit but some of the metabolites of s-ketamine also do contribute to the positive effects .

Regarding patents . It is possible to patent an ROA method just like what j&j did with s-ket




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