Ludomir Benedyktowicz (1844–1926) got his both hands chopped off at the age of 18 while fighting in a Polish uprising against Russia. This did not deter him from becoming a painter. You can see his low-tech prosthesis and a few of his paintings on Wikipedia[0].
Yeah, I got to know Benedyktowicz at the end of a long and winding experience that led me to read on the beginnings of the Krakow Chess Club (he was a founder). Depending on your outlook, it happened either by chance or by destiny.
[0] https://en.wikipedia.org/wiki/Ludomir_Benedyktowicz