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There is a big jump from "let's create some algorithms and data structures inspired by a simple model of the brain and see what kind of problems these algorithms are useful for" to "why doesn't our model fully and faithfully represent an actual brain".

The first of these questions has led to real progress in things like image recognition, whereas the second of these questions has not led any real progress in digitizing squirrel brains.



OpenWorm is, after years of work, up to nematode level.[1] Their WormSim is an emulation, at the neuron level, of the simplest creature whose nervous system has been fully mapped. 302 neurons, 25 muscle cells. Runs in a browser.

So true bottom-up is not hopeless.

[1] https://openworm.org/




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