Defect rates don't scale linearly to density IRL as you assume, and the type of defects changes as well. This is not the same as semiconductor manufacturing though plenty of parallels can be drawn.

>Do you have experience with e-ink panel manufacture?

I have deep insight in this industry due to my development experience with this tech. So the manufacturers tutor us on the nitty gritty details of the tech which stem from the manufacturing limitations, as my employers are making expensive purchases from them.

Of course, you are free to believe that I'm wrong and your kindergarten math is the answer to a profitable product to which the industry are completely oblivious too.