I've never gotten negative feedback in person on this, and negative feedback online for it is both rare and not something that bothers me much?
In general how much I care about feedback is weighted by some combination of how much I care about the person giving me the feedback and how important it seems. When someone on HN or elsewhere gives me feedback the former is low, so I'm mostly thinking about the latter. If the feedback is "you're wrong to be working on detecting novel pandemics because of detailed reasons XYZ" I'll take that quite seriously, but if it's just "you're a bad person for trying to earn a lot of money", especially without any sort of argument, I just ignore it.
In general how much I care about feedback is weighted by some combination of how much I care about the person giving me the feedback and how important it seems. When someone on HN or elsewhere gives me feedback the former is low, so I'm mostly thinking about the latter. If the feedback is "you're wrong to be working on detecting novel pandemics because of detailed reasons XYZ" I'll take that quite seriously, but if it's just "you're a bad person for trying to earn a lot of money", especially without any sort of argument, I just ignore it.