There's nothing in "modern" UI that cannot be done with Lazarus GUI Builder: Dynamic layouts? check,
anchors? check,
flexbox? check,
custom components? check
nested hierarchies of elements? HIDPI? check
Vector Graphics? check
Multiresolution? check
and so on.
All of them compiled to native (and looking native) on every platform under the sun.
As said before, GUI design peaked in the 90's