Yeah this is exactly what happens when you ask a base model a question. It'll just attempt to continue what you already wrote based off its training set, so if you say have it continue a story you've written it may wrap up the story and then ask you to subscribe for part 2, followed by a bunch of social media comments with reviews.
Considering "mixtral:8x22b" on ollama was last updated yesterday, and Mixtral-8x22B-Instruct-v0.1 (the topic of this post) was released about 2 hours ago, they are not the same model.
Mixtral-8x22B-v0.1 was released a couple days ago. The "mixtral:8x22b" tag on ollama currently refers to it, so it's what you got when you did "ollama run mixtral:8x22b". It's a base model only capable of text completion, not any other tasks, which is why you got a terrible result when you gave it instructions.
Mixtral-8x22B-Instruct-v0.1 is an instruction-following model based on Mixtral-8x22B-v0.1. It was released two hours ago and it's what this post is about.
(The last updated 44 minutes ago refers to the entire "mixtral" collection.)