Personally, I find astronomy quite depressing. Learning that humanity is stuck on this rock; at least for my lifetime if not forever. As a kid I dreamed of exploring space. As an adult I learned that is impossible.

I always knew I would see the first man on the moon. I never dreamed I would see the last. -- Jerry Eugene Pournelle

The term "observable universe" is depressing enough for me.

"Welp, that's enough of looking at tens of thousands of places I'll never see up close."

smashes telescope, grabs another beer, and buys some tickets to visit Spain before going to bed with a little bit less defeat and despair than usual