It could also be due to the EU's stricter pollution, chemical and food regulations compared to the US, the Brussels effect tends to make them apply globally to smaller markets.
I honestly think it could be as simple as being proportional with obesity, sedentary lifestyles, and sugar consumption that exist in the US and Canada.
The US and Canada really stand out specifically in their suburban infrastructure, which may strongly correlate with cancers in very obscure ways, such as simply needing more preservatives, such as sugars in bread, simply because people buy more in bulk because the culture of supermarkets.
I'll be honest, I think the chart needs a full explanation, but when I think of the US and Canada, and what makes them really unique, it's the complete lack of walking anywhere except the few urban centers.