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MDMA is not safe at all for rec use. It’s known to lesion the serotonergic system, even with a single dose. HED is always hard but if you compare the rat dosage they used with a typical 6-7x adjustment I think it comes in at not 150mg ish for a 175lb adult. Not that high relative to common dosing, especially if you’re a 98lb rave chick not a 175lb male.

Now factor in how hard it is to actually dose and the possible inclusion of other amphetamine analogs. Eg I’ve heard of para-chloro(meth)amphetamine showing up a few times, which is used intentionally as a neurotoxin to permanently destroy neurons.

And of course you have dysregulation of the brain’s temperature, magnified by the hot and high-cardio environments where MDMA is usually taken, which can be additionally neurotoxic.

If you synthesize your own or know someone who can, your risk is lower, but MDMA is simply not a safe thing to take.



Millions of people do it semi regularly.

They also do other unsafe things like drive cars and cross roads (anywhere in most countries where jay walking isn't a thing).


I didn't say it was likely to kill you, I said it was unsafe, that harm-reduction methods are wholly inadequate to making it safe, and that users should be aware of that. If people want to give informed consent to run those risks, be my guest, but "people do other unsafe things" 1. ignores that most of those don't directly cause brain damage, and 2. not all risky things are of equal risk, and brain damage is probably higher up than jay walking.




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