I liked the article a lot, thanks to the author for writing it and sharing it.
At that point, personally I think it'd be easier to use Preact with a no-build workflow for those bits of the app that have a lot of contained logic themselves, and don't necessarily require a round-trip to the server.
I've been building a largish webapp with htmx and I've leaned into web components for these more complicated interactions. I've found htmx great for everything that _should_ involve a call to the backend, anything that does need to fetch data or perform some crud operations, then i can return the necessary markup with oob swaps etc. and mostly forget about client side state
But yeah it's great to see people sharing their approaches!
At that point, personally I think it'd be easier to use Preact with a no-build workflow for those bits of the app that have a lot of contained logic themselves, and don't necessarily require a round-trip to the server.
I wouldn't use HTMX for that specific use case.