Highly recommend not doing this in production code. If nothing else, there's no compiler protection against offset+size being > total size, but one could add it with a static assert! (I've done so in the godbolt link)
You might want to have a look at the unboxing and packing annotations that are proposed for Virgil. The unboxing mechanism is implemented and there was a prototype of the packing mechanism implemented by Bradley for his thesis. I am working on making a more robust implementation that I can land.
I'm curious if some of the bits in your data types are "control bits" that determine what the format of the other bits are. If that's the case, then it sounds like an algebraic data type would be a natural way to express it. If you read the linked paper, algebraic datatypes in Virgil can have different encodings for the cases. As long as the cases are distinguishable via a decision tree, it should be possible to just describe the formats declaratively and have the compiler do all the encoding/decoding/matching.
Bitfields are kind of a fake feature because they can't be individually addressed like variables can. So they just turn into inlined getters and setters. Old compilers could not inline arbitrary short functions so bitfields were required as an extra hack, but this is no longer the case today.