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Thanks for the warning, I hope that it wasn't a personal experience for you.

Thanks for the compliment about the elaborate design. I think that when you make something for one or a few patients it is easier to be more elaborate, even with the same knowledge and equipment.

Maybe the TCR and BCR-seq was most helpful for mRNA design and effectiveness monitoring, but hopefully someone else on my team will answer that better.



The TCR sequencing has been helpful for downselecting TCRs for a TCR based cell therapy, and for monitoring response to various immune therapies (including the vaccines)


Interesting, thanks for your replies.

You should consider publishing a patient case report somewhere, as I believe there are lots of valuable conclusions to be extracted from your work.




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