Insulated windows? That would apply equally to any other system. Where care is required is sealing around whatever passes through the window.
As to the negative pressure, personally I just leave the door to the room cracked open very slightly. But if you have central heat ducts air will get sucked in through that no problem.
As to the negative pressure, personally I just leave the door to the room cracked open very slightly. But if you have central heat ducts air will get sucked in through that no problem.