I highly challenge this. For a region, industry booms drive upward movement. And regions that are only held by one industry when it busts build rust belts.

Ideally, you have industry for a region treated like a well balanced investment portfolio. But you have to internalize that balancing investment portfolios is is a protection against downside risks. And it specifically loses against the lucky portfolio that was heavy on something during a boom.

So, the question heavily looms on if the regions we are looking at are diverse enough that they can sustain some downturns.