The only scenario in which one could possibly argue this is if the option is using MV3 uBlock Origin Lite in basic mode, where the browser handles the content blocking just reading rules from uBoL.
uBO MV2 and MV3 in any of the higher two modes objectively add more attack surface when the alternative is basic uBoL + DNS level filtering which is the most secure combination second to just DNS-only filtering.
And ultimately ad blocking is only badness enumeration which is a poor security measure to rely on, especially when the main application (Firefox) lacks proper security measures versus Chromium. It’s like the NVIDIA owners coming up with 3,000 different cable solutions to the burning connectors when its a problem with the card itself.