I've been working remotely as a developer for a NYC startup for about 2.5 years now. There are a couple of other remote workers, with the rest of the team working in the office. My team has weekly meetings using webex, skype, etc and we mostly use IM and email for other communication. I make periodic visits to the NY office (I live in NC). I find that working remotely really agrees with my personality and work style. I am better able to focus for long periods and I don't really suffer from the social need for regular face to face contact with my co-workers. :) I also avoid a commute and I can spend time with my kids by just walking downstairs.