"Realizing this ROM hack is able to control the CPU with only the player’s inventory, [bortreb] wanted to see how far he could push this hack. He ended up writing a bootstrapping program by depositing and discarding items from the in-game PC, and was then able to reprogram the Game Boy with a number of button presses on the D-pad, select, start, A and B buttons."
Have you seen bortreb's pokemon hack?
http://hackaday.com/2012/11/24/programming-a-game-boy-while-...
"Realizing this ROM hack is able to control the CPU with only the player’s inventory, [bortreb] wanted to see how far he could push this hack. He ended up writing a bootstrapping program by depositing and discarding items from the in-game PC, and was then able to reprogram the Game Boy with a number of button presses on the D-pad, select, start, A and B buttons."