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Isn't clamAV[1] very good at this already and free of charge AND not keen to close an eye on specific signatures.

[1] http://www.clamav.net/doc/install.html

[2] http://www.clamxav.com for OSX



I believe Cisco now owns clamAV.


You don't have to use/trust the official database (or its whitelist). You could create a custom database with just the signatures you are interested in and run a scan with just that.




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