Render 3d graphics really fast? That's all I do that would begin to leverage that sort of power. Typically the two taxing things I do are play around with games and do 3d graphics/animation in Cinema 4D and AfterEffects. Games aren't built to make use of that many threads/cores or that much RAM but for graphics stuff, it would be like having my own little render farm in one workstation.
Well, actually making games requires that much power. I work at a games studio, run an 8-core(16-thread) Xeon + 64GB of ram + 1TB SSD and everything I do daily is just sloooow. Running the game in debug mode uses up all my ram, compilation times are between 20-40 minutes for the whole project even when using distributed build systems, and that 1TB SSD is not helping that much if it's nearly full all the time. If we could have our workstations upgraded to something like 16-core Xeons + 256GB of ram it would be a godsend.
